Name | Fmoc-L-Asn-OH |
Synonyms | Fmoc-Asn-OH Fmoc-L-Asn-OH Fmoc-L-asparagine Nalpha-Fmoc-L-Asparagine N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-asparagine (2S)-4-amino-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxobutanoate |
CAS | 71989-16-7 |
EINECS | 276-252-2 |
InChI | InChI=1/C19H18N2O5/c20-17(22)9-16(18(23)24)21-19(25)26-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16H,9-10H2,(H2,20,22)(H,21,25)(H,23,24)/p-1/t16-/m0/s1 |
Molecular Formula | C19H18N2O5 |
Molar Mass | 354.36 |
Density | 1.3354 (rough estimate) |
Melting Point | 180℃ |
Boling Point | 678.6°C at 760 mmHg |
Specific Rotation(α) | -13 ° (C=1, DMF) |
Flash Point | 364.2°C |
Vapor Presure | 2.43E-19mmHg at 25°C |
Appearance | White powder |
pKa | 3.68±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | -13 ° (C=1, DMF) |
MDL | MFCD00037132 |
Physical and Chemical Properties | Melting Point: 175 - 190 |
Use | Uses for polypeptide synthesis, as amino acid protection monomer. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 21 |
HS Code | 2924 29 70 |
Hazard Class | IRRITANT |
Raw Materials | Fluorene L-Asparagine Fmoc-N-trityl-L-asparagine 9-FLUORENYLMETHYL PENTAFLUOROPHENYL CARBONATE N-(9-Fluorenylmethoxycarbonyloxy)succinimide 9-Fluorenylmethyl chloroformate |
specific rotation | -13 ° (c=1,DMF) |
BRN | 4335103 |
Using fluorene methoxycarbonyl chloride (or azide) and L-asparagine as raw materials, recrystallized after acylation to obtain the finished product.